From: "Saved by Windows Internet Explorer 8" Subject: Jack W. Szostak, Ph.D. Date: Sat, 13 Sep 2008 13:26:13 +0200 MIME-Version: 1.0 Content-Type: multipart/related; type="text/html"; boundary="----=_NextPart_000_02DD_01C915A4.4B4988E0" X-MimeOLE: Produced By Microsoft MimeOLE V6.0.6000.16669 This is a multi-part message in MIME format. ------=_NextPart_000_02DD_01C915A4.4B4988E0 Content-Type: text/html; charset="utf-8" Content-Transfer-Encoding: quoted-printable Content-Location: http://www.hhmi.org/research/investigators/szostak_bio.html =EF=BB=BF Jack W. Szostak, Ph.D.
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Jack W. Szostak, Ph.D. =

3D"Jack=20

How did life begin? Scientists may never know = exactly=20 how a swirl of chemicals came together to form = the first=20 living organisms some 4 billion years ago, but = Jack=20 Szostak is working to recreate a hypothetical = model of=20 this process in the laboratory. By building = simple=20 cell-like structures in a test tube, he and his=20 colleagues are attempting to establish a = plausible path=20 that led primitive cells to emerge from simple=20 chemicals. Ultimately, Szostak hopes to answer=20 fundamental questions about evolution's earliest = steps.=20

At the outset of his career, Szostak made = pioneering=20 contributions to the field of genetics. His = discoveries=20 helped clarify the events that lead to = chromosomal=20 recombination=E2=80=94the reshuffling of genes = that occurs=20 during meiosis=E2=80=94and the function of = telomeres, the=20 specialized DNA sequences at the tips of = chromosomes. He=20 is also credited with the construction of the = world's=20 first yeast artificial chromosome. That feat = helped=20 scientists to map the location of genes in = mammals and=20 to develop techniques for manipulating genes. =

But a Nobel Prize=E2=80=93winning discovery = in the 1980s by=20 current HHMI President Tom Cech and Sidney = Altman=20 propelled Szostak down a new research path. The = pair=20 independently demonstrated that RNA, the sister = molecule=20 of DNA, can catalyze certain chemical reactions = inside=20 cells, a job previously thought to be the = exclusive=20 domain of proteins. Until then, RNA was thought = to have=20 just one function: storing the genetic = information cells=20 need to build proteins. This new revelation = about RNA's=20 dual role suggested to some scientists, = including=20 Szostak, that RNA likely existed long before DNA = or=20 proteins because it might be able to catalyze = its own=20 reproduction. Their discovery made it easier to = think=20 about the origin of life, Szostak says. "They = inspired=20 me to try to think of ways to make RNAs in the = lab that=20 could catalyze their own replication."

By 1991, Szostak had shifted the entire focus = of his=20 lab to evolving new functional RNAs and other = molecules=20 in a test tube. As the basis for his work, = Szostak=20 developed a technique called in vitro selection = to study=20 the evolution of biological molecules. This = method=20 screens vast numbers of molecules for a = predetermined=20 function, such as the ability to catalyze a = specific=20 chemical reaction or bind a target molecule. = Those that=20 don't fit the desired profile are filtered out = and the=20 process is repeated over and over again until=20 researchers find the molecule that does a = particular=20 job.

Using in vitro selection as a way to apply = the forces=20 of natural selection in a laboratory setting, = Szostak=20 and his colleagues evolved RNAs that bind to = ATP, a=20 common biological substrate, from a massive = library of=20 1,000 trillion random RNA sequences. Such = artificially=20 evolved RNAs that bind to target molecules are = now known=20 as aptamers, and they have many potential = applications=20 in the diagnosis and treatment of diseases and = as=20 biosensors. Szostak's team has also used in = vitro=20 selection to evolve catalytic RNAs, called = ribozymes,=20 from trillions of random-sequence RNA molecules. = "Many=20 new ribozymes have now been evolved by in vitro=20 selection," Szostak says. "The range of = chemistries=20 these artificially produced ribozymes can = catalyze is=20 much greater than that carried out by ribozymes = found in=20 living cells. It raises the interesting = possibility that=20 in an earlier era, ribozymes might have played a = wider=20 role than they do today." Szostak is also = investigating=20 in vitro selection for its ability to identify = small=20 molecules that bind specific target proteins. If = successful, the technique may provide a = streamlined way=20 to pinpoint potentially useful drugs to fight = disease.=20

Today, Szostak's main focus is the = construction of a=20 simple, artificial cell that can grow and divide = as well=20 as evolve in a Darwinian sense to adapt to its = changing=20 environment. To do this, he is attempting to = make and=20 then combine two self-replicating systems: a = nucleic=20 acid (such as RNA or DNA) that can transmit = genetic=20 information and a simple membrane-bound vesicle = that=20 keeps the nucleic acid chains from drifting = apart. A=20 major challenge is coordinating the growth and = division=20 of the membrane-bound vesicle with the = replication of=20 its contents. Szostak has found that the nucleic = acids=20 themselves can drive the growth of the fatty = acid=20 membrane; as they replicate, the internal = osmotic=20 pressure increases, swelling the vesicle and = stretching=20 the membrane so that it absorbs fatty acids from = other=20 vesicles that are under less internal pressure. = Cells=20 with faster nucleic acid replication should = therefore=20 grow faster than cells with slower nucleic acid=20 replication. In this way, simple physical = principles=20 coordinate the replication of the nucleic acid = genome=20 and the replication of the rest of the cell = structure,=20 leading to the emergence of natural selection = and=20 Darwinian evolution based on competition between = cells.

Dr. Szostak is also Professor of Genetics = at=20 Harvard Medical School and Alexander Rich = Distinguished=20 Investigator at Massachusetts General Hospital,=20 Boston.

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RESEARCH ABSTRACT=20 SUMMARY:

To increase understanding of the origin and = early=20 evolution of life, Jack Szostak explores the = origins of=20 functional biological macromolecules and = membranes.

View=20 Research Abstract3D"small=20

Photo: Mark Wilson

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HHMI INVESTIGATOR =
1998=E2=80=93Present =
Massachusetts General=20 Hospital

3DEducation=20
3D"bullet B.S., cell=20 biology, McGill University, Montreal,=20 Canada
3D"bullet Ph.D.,=20 biochemistry, Cornell=20 University
3DMember=20
3D"bullet National=20 Academy of Sciences
3D"bullet American=20 Academy of Arts and=20 Sciences
3D"bullet New York=20 Academy of Sciences
3DAwards=20
3D"bullet National=20 Academy of Sciences Award in Molecular=20 Biology
3D"bullet Hans Sigrist=20 Prize, University of Bern,=20 Switzerland
3D"bullet Genetics=20 Society of America = Medal
3D"bullet The 2006=20 Lasker Award
3D"bullet 2008 H.P.=20 Heineken Prize for Biochemistry and = Biophysics,=20 Royal Netherlands Academy of Arts and=20 Sciences

3D""=20 3D"Research 3D""=20
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The=20 Origins of Function in Biological Nucleic Acids, = Proteins, and=20 Membranes

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AT HHMI

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Researchers=20 Build Model Protocell Capable of Copying=20 DNA
(06.04.08)

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Simulating=20 Evolution: Artificial Enzymes Designed in the=20 Laboratory
(08.15.07)

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Lasker=20 Award for Basic Medical = Research
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Evo= lution=20 Is Our Laboratory

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Battle of=20 the Bubbles May Have Sparked = Evolution
(09.02.04)=20

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Clays May=20 Have Aided Formation of Primordial=20 Cells
(10.23.03)

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A=20 World Apart

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Evidence=20 that a Ribozyme Evolved Multiple = Times
(10.31.01)=20

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Researchers=20 Evolve New Proteins in the Test = Tube
(04.04.01)=20

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Th= e=20 2006 Lasker Award
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The=20 Szostak Lab
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COLOR: = #0aa5d2; FONT-SIZE: 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none; = PADDING-TOP: 5px } TD.topmenuitem:hover { PADDING-BOTTOM: 5px; BACKGROUND-COLOR: #e1f3ff; PADDING-LEFT: 8px; = PADDING-RIGHT: 8px; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #5b5b5b; FONT-SIZE: 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none; = PADDING-TOP: 5px } A.topmenuitem { PADDING-BOTTOM: 5px; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #0aa5d2; FONT-SIZE: 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none; = PADDING-TOP: 5px } A.topmenuitem:hover { PADDING-BOTTOM: 5px; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #5b5b5b; FONT-SIZE: 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none; = PADDING-TOP: 5px } .smallwhite { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #ffffff; FONT-SIZE: = 10px; FONT-WEIGHT: normal } A.smallwhite { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #ffffff; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smallwhite:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0d657f; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smallwhite:active { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #004551; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.mediumwhite { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #ffffff; FONT-SIZE: = 11px; FONT-WEIGHT: bold; TEXT-DECORATION: none } .orangefooter { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #eeb191; FONT-SIZE: = 10px; FONT-WEIGHT: normal } A.orangefooter { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #eeb191; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.orangefooter:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0d657f; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.orangefooter:active { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #004551; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } .smallorange { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #c46d47; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .smallorange B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #c46d47; FONT-SIZE: = 10px; FONT-WEIGHT: bold } .smallorange I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #c46d47; FONT-SIZE: 10px } A.smallorange { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #c46d47; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smallorange:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #c46d47; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smallorange:active { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #c46d47; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } .mediumorange { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #c46d47; FONT-SIZE: = 12px; FONT-WEIGHT: normal } .mediumorange B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #c46d47; FONT-SIZE: = 12px; FONT-WEIGHT: bold } .mediumorange I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #c46d47; FONT-SIZE: 12px } .smalllightorange { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #e3a084; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .smalllightorange B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #e3a084; FONT-SIZE: = 10px; FONT-WEIGHT: bold } .smalllightorange I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #e3a084; FONT-SIZE: 10px } .tourteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #84a09f; FONT-SIZE: = 10px; FONT-WEIGHT: normal } A.tourteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #84a09f; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.tourteal:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #eeb191; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } .tourorange { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #ffa679; FONT-SIZE: = 10px; FONT-WEIGHT: normal } A.tourorange { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #ffa679; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: underline } A.tourorange:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #ffffff; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: underline } .smallgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #999999; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .smallmedgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #999999; FONT-SIZE: = 11px; FONT-WEIGHT: normal } .smallbulletgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #757671; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .xlargebrown { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #8d7a6b; FONT-SIZE: = 16px; FONT-WEIGHT: bold } A.mediumwhite { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #ffffff; FONT-SIZE: = 11px; FONT-WEIGHT: bold; TEXT-DECORATION: none } .smallgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #999999; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .smallgrey I { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #999999; FONT-SIZE: = 10px; FONT-WEIGHT: normal } A.smallgrey B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #999999; FONT-SIZE: = 10px; FONT-WEIGHT: bold } A.smallgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #999999; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smallgrey:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smallgrey:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 10px; FONT-WEIGHT: bold; TEXT-DECORATION: none } .mediumgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #999999; FONT-SIZE: = 12px; FONT-WEIGHT: normal } .mediumgrey I { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #999999; FONT-SIZE: = 12px; FONT-WEIGHT: normal } .xlargegrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #999999; FONT-SIZE: = 16px; FONT-WEIGHT: bold } .xlargebrown { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #8d7a6b; FONT-SIZE: = 16px; FONT-WEIGHT: bold } .xlgdarkbrown { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #796a55; FONT-SIZE: = 26px; FONT-WEIGHT: normal } .darkbrown { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #796a55; FONT-SIZE: = 12px; FONT-WEIGHT: normal } .darkbrown B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #796a55; FONT-SIZE: = 12px; FONT-WEIGHT: bold } .darkbrown I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #796a55; FONT-SIZE: 12px } A.mediumgrey B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #999999; FONT-SIZE: = 12px; FONT-WEIGHT: bold } A.mediumgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #999999; FONT-SIZE: = 12px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.mediumgrey:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 12px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.mediumgrey:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 12px; FONT-WEIGHT: bold; TEXT-DECORATION: none } .crosslink { TEXT-TRANSFORM: uppercase; FONT-FAMILY: Verdana, Arial, San Serif; = COLOR: #0aa5d2; FONT-SIZE: 10px; FONT-WEIGHT: normal } A.crosslink { TEXT-TRANSFORM: uppercase; FONT-FAMILY: Verdana, Arial, San Serif; = COLOR: #0aa5d2; FONT-SIZE: 10px; FONT-WEIGHT: normal; TEXT-DECORATION: = none } A.crosslink:hover { TEXT-TRANSFORM: uppercase; FONT-FAMILY: Verdana, Arial, San Serif; = COLOR: #cc6600; FONT-SIZE: 10px; FONT-WEIGHT: normal; TEXT-DECORATION: = none } .smallteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #057778; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .smallteal B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #057778; FONT-SIZE: = 10px; FONT-WEIGHT: bold } .smalldarkteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5e9da7; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .smalldarkteal B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5e9da7; FONT-SIZE: = 10px; FONT-WEIGHT: bold } .smalldarkerteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #507f85; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .smalldarkerteal B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #507f85; FONT-SIZE: = 10px; FONT-WEIGHT: bold } .mediumdarkteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5e9da7; FONT-SIZE: = 12px; FONT-WEIGHT: normal } A.mediumteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #057778; FONT-SIZE: = 12px; FONT-WEIGHT: normal; TEXT-DECORATION: none } .mediumteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #057778; FONT-SIZE: = 12px; FONT-WEIGHT: normal } .mediumteal B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #057778; FONT-SIZE: = 12px; FONT-WEIGHT: bold } .largedarkteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5e9da7; FONT-SIZE: = 14px; FONT-WEIGHT: normal } .largedarkteal B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5e9da7; FONT-SIZE: = 14px; FONT-WEIGHT: bold } .darkerteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #336b7c; FONT-SIZE: = 12px; FONT-WEIGHT: normal } .darkerteal I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #336b7c; FONT-SIZE: 12px } .smalldarkerteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #336b7c; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .smalldarkerteal B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #336b7c; FONT-SIZE: = 10px; FONT-WEIGHT: bold } .smalldarkerteal I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #336b7c; FONT-SIZE: 10px } A.smalldarkerteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #336b7c; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smalldarkerteal:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #336b7c; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } .largeteal { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #057778; FONT-SIZE: = 14px; FONT-WEIGHT: normal } .largeteal B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #057778; FONT-SIZE: = 14px; FONT-WEIGHT: bold } .smallgreen { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #335c3e; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .smallgreen B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #335c3e; FONT-SIZE: = 10px; FONT-WEIGHT: bold } .smallgreen I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #335c3e; FONT-SIZE: 10px } .green { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #335c3e; FONT-SIZE: = 12px; FONT-WEIGHT: normal } .green B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #335c3e; FONT-SIZE: = 12px; FONT-WEIGHT: bold } .green I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #335c3e; FONT-SIZE: 12px } .smalllightgreen { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #81b090; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .smalllightgreen B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #81b090; FONT-SIZE: = 10px; FONT-WEIGHT: bold } .smalllightgreen I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #81b090; FONT-SIZE: 10px } .smalllightblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #80d2ea; FONT-SIZE: = 10px; FONT-WEIGHT: normal } A.smalllightblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #80d2ea; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smalllightblue:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #d38229; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smalllightblue B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #80d2ea; FONT-SIZE: = 10px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.smalllightblue:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #d38229; FONT-SIZE: = 10px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.smalllightblue I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #80d2ea; FONT-SIZE: 10px; TEXT-DECORATION: none } A.smalllightblue:hover I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #d38229; FONT-SIZE: 10px; TEXT-DECORATION: none } .smallblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 10px; FONT-WEIGHT: normal } A.smallblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smallblue:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smallblue B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 10px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.smallblue:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 10px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.smallblue I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #0aa5d2; FONT-SIZE: 10px; TEXT-DECORATION: none } A.smallblue:hover I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #cc6600; FONT-SIZE: 10px; TEXT-DECORATION: none } .smallmedblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 11px; FONT-WEIGHT: normal } A.smallmedblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 11px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smallmedblue:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 11px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smallmedblue B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 11px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.smallmedblue:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 11px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.smallmedblue I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #0aa5d2; FONT-SIZE: 11px; TEXT-DECORATION: none } A.smallmedblue:hover I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #cc6600; FONT-SIZE: 11px; TEXT-DECORATION: none } .mediumblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 12px; FONT-WEIGHT: normal } A.mediumblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 12px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.mediumblue B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 12px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.mediumblue I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #0aa5d2; FONT-SIZE: 12px; TEXT-DECORATION: none } A.mediumblue:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 12px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.mediumblue:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 12px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.mediumblue:hover I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #cc6600; FONT-SIZE: 12px; TEXT-DECORATION: none } .xlblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 16px; FONT-WEIGHT: bold } A.xlblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 16px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.xlblue B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 16px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.xlblue I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #0aa5d2; FONT-SIZE: 16px; TEXT-DECORATION: none } A.xlblue:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 16px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.xlblue:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 16px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.xlblue:hover I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #cc6600; FONT-SIZE: 16px; TEXT-DECORATION: none } .mediumdarkblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #238dac; FONT-SIZE: = 12px; FONT-WEIGHT: normal } A.smalldarkblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #238dac; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smalldarkblue B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #238dac; FONT-SIZE: = 10px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.smalldarkblue I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #238dac; FONT-SIZE: 10px; TEXT-DECORATION: none } A.smalldarkblue:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.smalldarkblue:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 10px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.smalldarkblue:hover I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #cc6600; FONT-SIZE: 10px; TEXT-DECORATION: none } .mediumdarkblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #238dac; FONT-SIZE: = 12px; FONT-WEIGHT: normal } A.mediumdarkblue { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #238dac; FONT-SIZE: = 12px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.mediumdarkblue B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #238dac; FONT-SIZE: = 12px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.mediumdarkblue I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #238dac; FONT-SIZE: 12px; TEXT-DECORATION: none } A.mediumdarkblue:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 12px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.mediumdarkblue:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #cc6600; FONT-SIZE: = 12px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.mediumdarkblue:hover I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #cc6600; FONT-SIZE: 12px; TEXT-DECORATION: none } .serifdarkblue { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #238dac; FONT-SIZE: = 18px; FONT-WEIGHT: normal } A.serifdarkblue { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #238dac; FONT-SIZE: = 18px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.serifdarkblue B { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #238dac; FONT-SIZE: = 18px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.serifdarkblue I { FONT-STYLE: italic; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #238dac; FONT-SIZE: 18px; TEXT-DECORATION: none } A.serifdarkblue:hover { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #cc6600; FONT-SIZE: = 18px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.serifdarkblue:hover B { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #cc6600; FONT-SIZE: = 18px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.serifdarkblue:hover I { FONT-STYLE: italic; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #cc6600; FONT-SIZE: 18px; TEXT-DECORATION: none } .seriflgdarkblue { LINE-HEIGHT: 29px; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #238dac; FONT-SIZE: 32px; FONT-WEIGHT: normal } A.seriflgdarkblue { LINE-HEIGHT: 29px; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #238dac; FONT-SIZE: 32px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.seriflgdarkblue B { LINE-HEIGHT: 29px; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #238dac; FONT-SIZE: 32px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.seriflgdarkblue I { LINE-HEIGHT: 29px; FONT-STYLE: italic; FONT-FAMILY: Times New Roman, = Times, Serif; COLOR: #238dac; FONT-SIZE: 32px; TEXT-DECORATION: none } A.seriflgdarkblue:hover { LINE-HEIGHT: 29px; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #cc6600; FONT-SIZE: 32px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.seriflgdarkblue:hover B { LINE-HEIGHT: 29px; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #cc6600; FONT-SIZE: 32px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.seriflgdarkblue:hover I { LINE-HEIGHT: 29px; FONT-STYLE: italic; FONT-FAMILY: Times New Roman, = Times, Serif; COLOR: #cc6600; FONT-SIZE: 32px; TEXT-DECORATION: none } .serifxldarkblue { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #238dac; FONT-SIZE: = 36px; FONT-WEIGHT: normal } A.serifxldarkblue { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #238dac; FONT-SIZE: = 36px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.serifxldarkblue B { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #238dac; FONT-SIZE: = 36px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.serifxldarkblue I { FONT-STYLE: italic; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #238dac; FONT-SIZE: 36px; TEXT-DECORATION: none } A.serifxldarkblue:hover { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #cc6600; FONT-SIZE: = 36px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.serifxldarkblue:hover B { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #cc6600; FONT-SIZE: = 36px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.serifxldarkblue:hover I { FONT-STYLE: italic; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #cc6600; FONT-SIZE: 36px; TEXT-DECORATION: none } .greytouthead { TEXT-TRANSFORM: uppercase; FONT-FAMILY: Verdana, Arial, San Serif; = COLOR: #8f8f8f; FONT-SIZE: 10px; FONT-WEIGHT: normal } .sciPosition { TEXT-TRANSFORM: uppercase; FONT-FAMILY: Verdana, Arial, San Serif; = COLOR: #5b5b5b; FONT-SIZE: 10px; FONT-WEIGHT: normal } .sciPosition B { TEXT-TRANSFORM: uppercase; FONT-FAMILY: Verdana, Arial, San Serif; = COLOR: #5b5b5b; FONT-SIZE: 10px; FONT-WEIGHT: bold } .sciPosition I { TEXT-TRANSFORM: uppercase; FONT-STYLE: italic; FONT-FAMILY: Verdana, = Arial, San Serif; COLOR: #5b5b5b; FONT-SIZE: 10px } A.sciPosition { TEXT-TRANSFORM: uppercase; FONT-FAMILY: Verdana, Arial, San Serif; = COLOR: #5b5b5b; FONT-SIZE: 10px; FONT-WEIGHT: normal; TEXT-DECORATION: = none } A.sciPosition:hover { TEXT-TRANSFORM: uppercase; FONT-FAMILY: Verdana, Arial, San Serif; = COLOR: #0aa5d2; FONT-SIZE: 10px; FONT-WEIGHT: normal; TEXT-DECORATION: = none } A.sciPosition:hover B { TEXT-TRANSFORM: uppercase; FONT-FAMILY: Verdana, Arial, San Serif; = COLOR: #0aa5d2; FONT-SIZE: 10px; FONT-WEIGHT: bold; TEXT-DECORATION: = none } .smalldarkgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5b5b5b; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .smalldarkgrey I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #5b5b5b; FONT-SIZE: 10px } A.smalldarkgrey B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5b5b5b; FONT-SIZE: = 10px; FONT-WEIGHT: bold } .darkgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5b5b5b; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .darkgrey B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5b5b5b; FONT-SIZE: = 10px; FONT-WEIGHT: bold } .darkgrey I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #5b5b5b; FONT-SIZE: 10px } A.darkgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5b5b5b; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.darkgrey:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.darkgrey:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 10px; FONT-WEIGHT: bold; TEXT-DECORATION: none } .darkgrey2 { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5e5a55; FONT-SIZE: = 10px; FONT-WEIGHT: normal } .darkgrey2 B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5e5a55; FONT-SIZE: = 10px; FONT-WEIGHT: bold } .darkgrey2 I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #5e5a55; FONT-SIZE: 10px } A.darkgrey2 { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5e5a55; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.darkgrey2:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5e5a55; FONT-SIZE: = 10px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.darkgrey2:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5e5a55; FONT-SIZE: = 10px; FONT-WEIGHT: bold; TEXT-DECORATION: none } .largedarkgrey B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5b5b5b; FONT-SIZE: = 16px; FONT-WEIGHT: bold } .largedarkgrey I { FONT-STYLE: italic; FONT-FAMILY: Verdana, Arial, San Serif; COLOR: = #5b5b5b; FONT-SIZE: 16px } .largedarkgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5b5b5b; FONT-SIZE: = 16px; FONT-WEIGHT: normal } .largedarkgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5b5b5b; FONT-SIZE: = 11px; FONT-WEIGHT: normal } .largedarkergrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #353535; FONT-SIZE: = 11px; FONT-WEIGHT: normal } .largedarkergrey I { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #353535; FONT-SIZE: 11px } A.largedarkgrey { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #5b5b5b; FONT-SIZE: = 16px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.largedarkgrey:hover { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 16px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.largedarkgrey:hover B { FONT-FAMILY: Verdana, Arial, San Serif; COLOR: #0aa5d2; FONT-SIZE: = 16px; FONT-WEIGHT: bold; TEXT-DECORATION: none } .seriflggrey { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #5e5a55; FONT-SIZE: = 17px; FONT-WEIGHT: normal } A.seriflggrey { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #5e5a55; FONT-SIZE: = 17px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.seriflggrey B { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #5e5a55; FONT-SIZE: = 17px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.seriflggrey I { FONT-STYLE: italic; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #5e5a55; FONT-SIZE: 17px; TEXT-DECORATION: none } A.seriflggrey:hover { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #5e5a55; FONT-SIZE: = 17px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.seriflggrey:hover B { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #5e5a55; FONT-SIZE: = 17px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.seriflggrey:hover I { FONT-STYLE: italic; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #5e5a55; FONT-SIZE: 17px; TEXT-DECORATION: none } .serifmedgrey { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #5e5a55; FONT-SIZE: = 12px; FONT-WEIGHT: normal } A.serifmedgrey { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #5e5a55; FONT-SIZE: = 12px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.serifmedgrey B { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #5e5a55; FONT-SIZE: = 12px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.serifmedgrey I { FONT-STYLE: italic; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #5e5a55; FONT-SIZE: 12px; TEXT-DECORATION: none } A.serifmedgrey:hover { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #5e5a55; FONT-SIZE: = 12px; FONT-WEIGHT: normal; TEXT-DECORATION: none } A.serifmedgrey:hover B { FONT-FAMILY: Times New Roman, Times, Serif; COLOR: #5e5a55; FONT-SIZE: = 12px; FONT-WEIGHT: bold; TEXT-DECORATION: none } A.serifmedgrey:hover I { FONT-STYLE: italic; FONT-FAMILY: Times New Roman, Times, Serif; COLOR: = #5e5a55; FONT-SIZE: 12px; TEXT-DECORATION: none } INPUT.search { BORDER-BOTTOM: #5e5a55 1px solid; BORDER-LEFT: #5e5a55 1px solid; = PADDING-BOTTOM: 1px; BACKGROUND-COLOR: #ffffff; WIDTH: 125px; = FONT-FAMILY: Verdana, Arial, San Serif; HEIGHT: 14px; FONT-SIZE: 9px; = BORDER-TOP: #5e5a55 1px solid; BORDER-RIGHT: #5e5a55 1px solid; = PADDING-TOP: 1px } INPUT.emailstory { BORDER-BOTTOM: #5e5a55 1px solid; BORDER-LEFT: #5e5a55 1px solid; = PADDING-BOTTOM: 1px; BACKGROUND-COLOR: #ffffff; WIDTH: 180px; = FONT-FAMILY: Verdana, Arial, San Serif; HEIGHT: 20px; FONT-SIZE: 10px; = BORDER-TOP: #5e5a55 1px solid; BORDER-RIGHT: #5e5a55 1px solid; = PADDING-TOP: 1px } INPUT.smallest { BORDER-BOTTOM: #5e5a55 1px solid; BORDER-LEFT: #5e5a55 1px solid; = PADDING-BOTTOM: 1px; BACKGROUND-COLOR: #ffffff; WIDTH: 50px; = FONT-FAMILY: Verdana, Arial, San Serif; HEIGHT: 20px; FONT-SIZE: 10px; = BORDER-TOP: #5e5a55 1px solid; BORDER-RIGHT: #5e5a55 1px solid; = PADDING-TOP: 1px } INPUT.small { BORDER-BOTTOM: #5e5a55 1px solid; BORDER-LEFT: #5e5a55 1px solid; = PADDING-BOTTOM: 1px; BACKGROUND-COLOR: #ffffff; WIDTH: 125px; = FONT-FAMILY: Verdana, Arial, San Serif; HEIGHT: 20px; FONT-SIZE: 10px; = BORDER-TOP: #5e5a55 1px solid; BORDER-RIGHT: #5e5a55 1px solid; = PADDING-TOP: 1px } INPUT.medium { BORDER-BOTTOM: #5e5a55 1px solid; BORDER-LEFT: #5e5a55 1px solid; = PADDING-BOTTOM: 1px; BACKGROUND-COLOR: #ffffff; WIDTH: 152px; = FONT-FAMILY: Verdana, Arial, San Serif; HEIGHT: 20px; FONT-SIZE: 10px; = BORDER-TOP: #5e5a55 1px solid; BORDER-RIGHT: #5e5a55 1px solid; = PADDING-TOP: 1px } INPUT.large { BORDER-BOTTOM: #5e5a55 1px solid; BORDER-LEFT: #5e5a55 1px solid; = PADDING-BOTTOM: 1px; BACKGROUND-COLOR: #ffffff; WIDTH: 225px; = FONT-FAMILY: Verdana, Arial, San Serif; HEIGHT: 20px; FONT-SIZE: 10px; = BORDER-TOP: #5e5a55 1px solid; BORDER-RIGHT: #5e5a55 1px solid; = PADDING-TOP: 1px } INPUT.largest { BORDER-BOTTOM: #5e5a55 1px solid; BORDER-LEFT: #5e5a55 1px solid; = PADDING-BOTTOM: 1px; BACKGROUND-COLOR: #ffffff; WIDTH: 320px; = FONT-FAMILY: Verdana, Arial, San Serif; HEIGHT: 20px; FONT-SIZE: 10px; = BORDER-TOP: #5e5a55 1px solid; BORDER-RIGHT: #5e5a55 1px solid; = PADDING-TOP: 1px } TEXTAREA { BORDER-BOTTOM: #5e5a55 1px solid; BORDER-LEFT: #5e5a55 1px solid; = PADDING-BOTTOM: 1px; BACKGROUND-COLOR: #ffffff; FONT-FAMILY: Verdana, = Arial, San Serif; FONT-SIZE: 10px; BORDER-TOP: #5e5a55 1px solid; = BORDER-RIGHT: #5e5a55 1px solid; PADDING-TOP: 1px } SELECT { BORDER-BOTTOM: #5e5a55 1px solid; BORDER-LEFT: #5e5a55 1px solid; = PADDING-BOTTOM: 1px; BACKGROUND-COLOR: #ffffff; FONT-FAMILY: Verdana, = Arial, San Serif; FONT-SIZE: 10px; BORDER-TOP: #5e5a55 1px solid; = BORDER-RIGHT: #5e5a55 1px solid; PADDING-TOP: 1px } .menuitem { PADDING-BOTTOM: 5px; BACKGROUND-COLOR: #ffffff; PADDING-LEFT: 5px; = PADDING-RIGHT: 5px; PADDING-TOP: 5px } .topmenudiv { BACKGROUND-COLOR: #bdbdba } .greenlogobg { BACKGROUND-COLOR: #42a960 } .darkgreenlogobg { BACKGROUND-COLOR: #3b9455 } .darkgreenbg { BACKGROUND-COLOR: #2e8444 } .lightgreenbg { BACKGROUND-COLOR: #bed8d0 } .lightgreyborder { BACKGROUND-COLOR: #b9b7ad } .greybg { BACKGROUND-COLOR: #d3d3d3 } .darkgreybg { BACKGROUND-COLOR: #4c4843 } .whitebg { BACKGROUND-COLOR: #ffffff } SPAN.greek { FONT-FAMILY: Symbol; COLOR: #353535; FONT-SIZE: 12px; FONT-WEIGHT: = normal; TEXT-DECORATION: none } ------=_NextPart_000_02DD_01C915A4.4B4988E0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.hhmi.org/js/about.js var HHMIBubble, HHMINavPop;=0A= =0A= var currentNavURL;=0A= =0A= =0A= =0A= self.onerror =3D function() {=0A= =0A= return true;=0A= =0A= }=0A= =0A= function di(id,name){=0A= =0A= if (document.images) {document.images[id].src=3Deval(name+".src"); }=0A= =0A= }=0A= =0A= =0A= =0A= // function that displays status bar message=0A= =0A= =0A= =0A= function dm(msgStr) {=0A= =0A= document.returnValue =3D false;=0A= =0A= if (document.images) { =0A= =0A= window.status =3D msgStr;=0A= =0A= document.returnValue =3D true;=0A= =0A= }=0A= =0A= }=0A= =0A= var showMsg =3D navigator.userAgent !=3D "Mozilla/4.0 (compatible; MSIE = 4.0; Mac_PowerPC)";=0A= =0A= function dmim(msgStr) {=0A= =0A= document.returnValue =3D false;=0A= =0A= if (showMsg) { =0A= =0A= window.status =3D msgStr;=0A= =0A= document.returnValue =3D true;=0A= =0A= }=0A= =0A= }=0A= =0A= =0A= =0A= function setNav(navURL) {=0A= =0A= if (navURL !=3D currentNavURL) {=0A= =0A= parent.nav.location.href=3DnavURL;=0A= =0A= }=0A= =0A= }=0A= =0A= =0A= =0A= function setContent(contentURL) {=0A= =0A= parent.content.location.href=3DcontentURL;=0A= =0A= }=0A= =0A= =0A= =0A= /*=0A= =0A= // function that safely loads the main window with URL and closes the = current bubble=0A= =0A= function burstBubble(URL) {=0A= =0A= if ((HHMIBubble !=3D undefined) && (HHMIBubble.close !=3D undefined)) {=0A= =0A= if (HHMIBubble.opener) {=0A= =0A= HHMIBubble.opener.location =3D URL;=0A= =0A= HHMIBubble.close();=0A= =0A= }=0A= =0A= }=0A= =0A= }=0A= =0A= */=0A= =0A= =0A= =0A= // function that will load the bubble with URL, opening the bubble if = necessary (one bubble per page)=0A= =0A= function loadBubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dyes,width=3D468,height=3D560'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= // function that will load the bubble with URL, opening the bubble if = necessary) =0A= =0A= function loadFigaBubble(URL) {=0A= self.name =3D "hhminews";=0A= HHMIStoreBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3Dno,location=3Dno,directories=3Dno,status=3Dno,scrollbars=3Dyes= ,resizable=3Dyes,width=3D420,height=3D650'); =0A= HHMIStoreBubble.focus(); =0A= =0A= }=0A= =0A= // function that will load the bubble with URL, opening the bubble if = necessary (one bubble per page)=0A= =0A= function loadWideBubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dyes,width=3D640,height=3D440'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= // function that will load the bubble with URL, opening the bubble if = necessary (one bubble per page)=0A= =0A= function loadHrBubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D0,resiz= able=3Dyes,width=3D350,height=3D480'); =0A= HHMIBubble.focus(); =0A= =0A= }=0A= =0A= // function that will load the bubble with URL, opening the bubble if = necessary (one bubble per page)=0A= =0A= function load755Bubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dyes,width=3D755,height=3D705'); =0A= HHMIBubble.focus(); =0A= =0A= }=0A= =0A= // function that will load the bubble with URL, opening the bubble if = necessary (one bubble per page)=0A= =0A= function load940Bubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dyes,width=3D940,height=3D540'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= // function that will load the bubble with URL, opening the bubble if = necessary (one bubble per page)=0A= =0A= function loadNavBubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3Dyes,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,res= izable=3Dyes,width=3D600,height=3D570'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= // function that will load the bubble with URL, opening the bubble if = necessary (one bubble per page)=0A= =0A= function load525Bubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dyes,width=3D525,height=3D525'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= function load550Bubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dyes,width=3D550,height=3D750'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= // function that safely closes the bubble=0A= =0A= function load630sqBubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D0,resiz= able=3Dyes,width=3D630,height=3D630'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= function load660sqBubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D0,resiz= able=3Dyes,width=3D660,height=3D660'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= function load680rectBubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dyes,width=3D680,height=3D800'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= function load330Bubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dyes,width=3D330,height=3D540'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= function loadAudioBubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dyes,width=3D330,height=3D50'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= function loadVideoBubble(URL) {=0A= self.name =3D "hhmiabout";=0A= HHMIBubble =3D window.open(URL, window.name+'bubble', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dyes,width=3D350,height=3D300'); =0A= HHMIBubble.focus();=0A= }=0A= =0A= // function that safely closes the bubble=0A= =0A= function closeBubble() {=0A= =0A= if ((HHMIBubble !=3D undefined) && (HHMIBubble.close !=3D undefined)) {=0A= =0A= HHMIBubble.close();=0A= =0A= }=0A= =0A= }=0A= =0A= =0A= =0A= // function that (re)opens a navpop with URL (one navpop per page)=0A= =0A= function loadNavPop(URL) {=0A= =0A= HHMINavPop =3D window.open(URL, window.name+'navpop', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,scrollbars=3D1,resiz= able=3Dno,width=3D340,height=3D350'); =0A= =0A= HHMINavPop.focus();=0A= =0A= }=0A= =0A= =0A= =0A= // function that safely loads and focuses on the main window with URL=0A= =0A= function loadMain(URL) {=0A= =0A= if (window.opener) {=0A= =0A= window.opener.location =3D URL;=0A= =0A= window.opener.focus();=0A= =0A= }=0A= =0A= }=0A= =0A= ------=_NextPart_000_02DD_01C915A4.4B4988E0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.hhmi.org/js/fsrscripts/triggerParams.js // Customer: Howard Hughes Medical Institute // Version : DHTML Trigger 3.2.3 function cppUrlPatch(s) { var translated =3D ""; var i;=20 var found =3D 0; for(i =3D 0; (found =3D s.indexOf(':', found)) !=3D -1; ) { translated +=3D s.substring(i, found) + "|"; i =3D found + 1; found++; } translated +=3D s.substring(i, s.length); return translated; } var triggerParms =3D new Array();=20 var excludeList =3D new Array(); var flashTagList=3D new Array(); triggerParms["displayMode"] =3D 1; //0=3Ddisable, 1=3Ddefault popup then = dhtml, 2=3Dpopup only, 3=3Ddhtml only triggerParms["mid"] =3D "M5IwhphcNVF0sgldxBpo1Q=3D=3D"; // model = instance id triggerParms["cid"] =3D "45lo1FZhVxBAhk4MYpFcRw=3D=3D"; // customer id triggerParms["lf"] =3D 4; // loyalty factor triggerParms["sp"] =3D 9; // sample percentage triggerParms["npc"] =3D 0; // no persistent cookies if 1 triggerParms["rw"] =3D 129600; // resample wait (value in minutes) triggerParms["pu"] =3D 0; // pop-under control triggerParms["olpu"] =3D 1; // On Load pop-under control triggerParms["lfcookie"] =3D "ForeseeLoyalty_MID_M5IwhphcNV"; triggerParms["ascookie"] =3D "ForeseeSurveyShown_M5IwhphcNV"; triggerParms["width"] =3D 450; // survey width triggerParms["height"] =3D 500; // survey height triggerParms["domain"] =3D ".hhmi.org"; // domain name triggerParms["omb"] =3D "1505-0186"; // OMB number //triggerParms["cmetrics"] =3D "90010257"; // coremetrics client id triggerParms["visualScienceId"] =3D 0; // enable visual science code if = 1 triggerParms["omnitureId"] =3D 0; // enable omniture code if 1 triggerParms["cpp_1"] =3D "userURL:" + cppUrlPatch = (window.location.href); //triggerParms["cpp_5"] =3D "cpp_name:"+ cppUrlPatch("cpp_value"); //a = placeholder for customer CPP's triggerParms["capturePageView"] =3D 1; //excludeList[0] =3D "/exclude/"; //trigger script will not work under = this path //triggerParms["dcUniqueId"] =3D "TEST04JloZZN0k9cI1Ep5d"; // (22 chars = unique Id for double cookie I/II) //triggerParms["midexp"] =3D 129600; // model instance expiry value triggerParms["rso"]=3D 0; //user has chosen to use Retry Survey Option triggerParms["aro"]=3D 0; //user has chosen to use Auto Retry Option, = with SP=3D100 //triggerParms["rct"]=3D 1; //The maximum number of times allowed to = serve a survey to a user //triggerParms["rds"]=3D 1; //The minimum number of days to wait to = serve a survey repeatedly //triggerParms["mrd"]=3D 1; //The total number of days that a user can = be re-served a survey triggerParms["compliant508"] =3D 1; //508 compliant if 1 //DHTML Parameters triggerParms["dhtmlIndex"]=3D 100; // z-index s/b greater then = client=92s dhtml z-index (if exist) - default 100 triggerParms["dhtmlWidth"] =3D 400; // welcome page width triggerParms["dhtmlHeight"] =3D 290; // welcome page height triggerParms["dhtmlURL"]=3D "/js/fsrscripts/FSRInvite.html"; //DHTML Positioning //center bottom-center bottom-right bottom-left upper-right = upper-left //x,y =3D (2,150) x,y =3D (2,350) x,y =3D (1.02,350) x,y =3D (60,350) = x,y =3D (1.02,50) x,y =3D (60,50) //replace (x,y) below with any one of the above, default =3D center var x=3D2; var y=3D150; triggerParms["dhtmlLeft"] =3D (self.screen.width - = triggerParms["dhtmlWidth"])/x; //invite page left position**DO NOT = MODIFY** triggerParms["dhtmlTop"] =3D Math.min((self.screen.height - = triggerParms["dhtmlHeight"])/2,y); //invite page top position**DO NOT = MODIFY** //FLASH Parameters - not to be used with other embedded objects e.g. = (.dcr/.mov/.mpeg/.avi/.wma/.wmv/.aam/.rm/.ram) triggerParms["flashDetect"]=3D 0; // check if page has flash embedded = with a valid browser & player ver before showing dhtml - disable if 0 flashTagList[0]=3D "swf"; // flash src check for IE/NE complaint = browsers flashTagList[1]=3D "spl"; // splash src check for IE/NE complaint = browsers flashTagList[2]=3D "clsid:d27cdb6e-ae6d-11cf-96b8-444553540000"; = //activeX ID check for IE browsers only triggerParms["inviteDelay"]=3D 1000; // invite timeout in millisecs - = default 1000ms=3D1sec //List of Multiple Survey Vendors - uncomment variables below & add = corresponding SP and URL //var multiVendorSP=3D new Array(); //var multiVendorURL=3D new Array(); //multiVendorSP[0] =3D 0; // sampling percentage for another vendor - = disable if commented //multiVendorURL[0] =3D ""; // absolute path to the third-party script - = disable if commented //Foresee System Paramters triggerParms["captureTriggerVersion"] =3D "STD3.2.3"; // track latest = trigger version triggerParms["popupURL"] =3D "//www.foreseeresults.com/survey/display"; = //do not change this url unless notified. triggerParms["FSRImgURL"]=3D "//www.foreseeresults.com/survey/FSRImg"; = //do not change this url unless notified. ------=_NextPart_000_02DD_01C915A4.4B4988E0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.hhmi.org/js/fsrscripts/stdLauncher.js /************ don't modify below this line ********* ************* = Version : DHTML Trigger 3.2.3 ****** ****** Copyright 2001-2006 = ForeseeResults, Inc****/ var OTCImgURL =3D = "//controller.foreseeresults.com/fsrSurvey/OTCImg"; var ckAlreadyShown = =3D triggerParms["ascookie"]; /* name of the persistent/session cookie*/ = var ckLoyaltyCount =3D triggerParms["lfcookie"]; /* name of the loyalty = count cookie*/ var fullURL=3Dnull; var myPopUp=3Dnull; var = fsr_mac=3Dnull; var fsr_aol=3Dnull; var fsr_opera=3Dnull; var = fsr_NS8=3Dnull; /*used in Invite Page to show Note for Netscape 8 = browsers only*/ var fsr_ie=3D0; var flash_version=3D 4; /*supports flash = version 4 and above in IE only*/ var canFlashPlay=3D0; var = dcQString=3D""; var cpp_3 =3D ""; var winOptions =3D = "toolbar=3D0,scrollbars=3D1,location=3D0,statusbar=3D0,menubar=3D0,resiza= ble=3D1,width=3D1,height=3D1,top=3D4000,left=3D4000"; var = persistentExpires =3D new Date(); /*persistent cookie expiration*/ = persistentExpires.setTime(persistentExpires.getTime() + = (triggerParms["rw"]*60*1000)); var detect =3D = navigator.userAgent.toLowerCase(); var version=3D = navigator.appVersion.toLowerCase(); /* FOR MSIE BASED BROWSERS ONLY - = detect Flash Plugin & Version*/ if (detect && = detect.indexOf("msie")>=3D0 && (version.indexOf("win") !=3D -1) && = triggerParms["flashDetect"] =3D=3D 1) { fsr_ie=3D1; = document.write(' \n'); = document.write('on error resume next \n'); document.write('canFlashPlay = =3D ( IsObject(CreateObject("ShockwaveFlash.ShockwaveFlash." & = flash_version)))\n'); document.write(' \n'); } function = ForeCStdGetCookie (name) { var arg =3D name + "=3D"; var alen =3D = arg.length; var clen =3D document.cookie.length; var i =3D 0; while (i < = clen) { var j =3D i + alen; if (document.cookie.substring(i, j) =3D=3D = arg) { return ForeCStdGetCookieVal (j); } i =3D = document.cookie.indexOf(" ", i) + 1; if (i =3D=3D 0) { break; } } return = null; } function fsr_showWindow() { if(myPopUp !=3D null && = !myPopUp.closed && fsr_aol=3D=3Dfalse && fsr_opera=3D=3Dfalse) {return;} = var cpp3Str =3D ""; cpp_3 =3D "Browser:"+ cppUrlPatch (detect) + ";" + = triggerParms["captureTriggerVersion"]; cpp_3+=3D";dhtml"; var pos1 =3D = fullURL.indexOf("&cpp_3=3D"); var pos2 =3D fullURL.indexOf("&",pos1+1); = if (pos2=3D=3D-1){ fullURL =3D fullURL.substring(0,pos1); }else{ cpp3Str = =3D fullURL.substring(pos2,fullURL.length); fullURL =3D = fullURL.substring(0,pos1); } fullURL+=3D"&cpp_3=3D"+cpp_3 + cpp3Str; = if(document.all && document.all.fsr_window.filters) { = eval("document.all.fsr_window").filters.revealTrans.transition =3D 23 ; = eval("document.all.fsr_window").filters.revealTrans.Apply(); = eval("document.all.fsr_window").style.visibility =3D 'visible'; = eval("document.all.fsr_window").filters.revealTrans.Play(); } else = if(document.all) {document.all.fsr_window.style.visibility =3D = 'visible';} else if(document.getElementById) = {document.getElementById("fsr_window").style.visibility =3D 'visible';} = } function fsr_hideWindow() { if(document.all && = document.all.fsr_window.filters) { = eval("document.all.fsr_window").filters.revealTrans.transition =3D 23; = eval("document.all.fsr_window").filters.revealTrans.Apply(); = eval("document.all.fsr_window").style.visibility =3D 'hidden'; = eval("document.all.fsr_window").filters.revealTrans.Play(); } else = if(document.all) {document.all.fsr_window.style.visibility =3D = 'hidden';} else if(document.getElementById) = {document.getElementById("fsr_window").style.visibility =3D 'hidden';} } = function ForeCStdSetCookie (name, value) { var argv =3D = ForeCStdSetCookie.arguments; var argc =3D = ForeCStdSetCookie.arguments.length; var expires =3D (argc > 2) ? argv[2] = : null; var path =3D (argc > 3) ? argv[3] : null; var domain =3D (argc > = 4) ? argv[4] : null; var secure =3D (argc > 5) ? argv[5] : false; = document.cookie =3D name + "=3D" + escape (value) + ((expires =3D=3D = null) ? "" : ("; expires=3D" + expires.toGMTString())) + ((path =3D=3D = null) ? "" : ("; path=3D" + path)) + ((domain =3D=3D null) ? "" : ("; = domain=3D" + domain)) + ((secure =3D=3D true) ? "; secure" : ""); } = function ForeCStdGetCookieVal(offset) { var endstr =3D = document.cookie.indexOf (";", offset); if (endstr =3D=3D -1) { endstr = =3D document.cookie.length; } return = unescape(document.cookie.substring(offset, endstr)); } function = specialEscape(str) { var translated =3D ""; var i; var found =3D 0; = for(i =3D 0; (found =3D str.indexOf('+', found)) !=3D -1; ) { translated = +=3D str.substring(i, found) + "%2B"; i =3D found + 1; found++; } = translated +=3D str.substring(i, str.length); return translated; } = function Pop(){ myPopUp =3D window.open(fullURL, "survey",winOptions); = if ( myPopUp!=3Dnull && !myPopUp.closed) { if (triggerParms["pu"] =3D=3D = 1){self.focus(); } else { myPopUp.focus(); } } } function = currentLocationExcluded() { var parentURLPath =3D = window.location.pathname;/*location path*/ for(key in excludeList) { = if(parentURLPath.indexOf(excludeList[key]) !=3D -1) { return true; } } = return false; } var newDt; var currTime; /*in millisecs*/ var OTCImg; = var FSRImg; var surveyProcessCont =3D 1; function stdImgProc() { = if(triggerParms["compliant508"] =3D=3D 1) { fsr_showWindow();} else { = setTimeout("fsr_showWindow();", = triggerParms["inviteDelay"],"JavaScript"); } } function fsrShowSurvey(){ = if(dcQString =3D=3D "") { stdImgProc(); } else { newDt =3D new Date(); = currTime=3D newDt.getTime(); /*in millisecs*/ FSRImg =3D new Image(); = FSRImg.src =3D null; FSRImg.onerror =3D imgErrorProc; FSRImg.onload =3D = imgOnloadProc; FSRImg.src =3D triggerParms["FSRImgURL"] + "?" + = dcQString + "&uid=3D"+ currTime; /*for NE/FF Cache Fix*/ } } function = imgOnloadProc() { if(surveyProcessCont =3D=3D 1 && FSRImg.width =3D=3D = 3) { stdImgProc(); } return true; } function imgErrorProc() { = surveyProcessCont =3D 0; return true; } function otcOnloadProc() { = if(surveyProcessCont =3D=3D 1 && OTCImg.width =3D=3D 3) { = fsrShowSurvey(); } else { surveyProcessCont =3D 0; } return true; } = function otcErrorProc() { fsrShowSurvey(); return true; } function = setVisualSciencesId(theURL) { var VisualSciencesId =3D = ForeCStdGetCookie("v1st"); if(VisualSciencesId !=3D null && = VisualSciencesId !=3D "") { triggerParms["cpp_4"] =3D = "VisualSciencesId:" + escape(VisualSciencesId); } } function = setOmnitureId(theURL) { var OmnitureId =3D = ForeCStdGetCookie("s_foreSeeId"); if(OmnitureId !=3D null && OmnitureId = !=3D "") { triggerParms["cpp_0"] =3D "OmnitureId:" + escape(OmnitureId); = } } function checkFlashParms(tagName){ tagName =3D = tagName.toLowerCase(); for(key in flashTagList) { = if(tagName.indexOf(flashTagList[key]) !=3D -1) { return true; } } return = false; } function fsr_detectFlash(){ if (fsr_ie){ /** For IE Compatible = browsers **/ var obj =3D document.all.tags("OBJECT"); for (var e=3D0; = e=3D0) ? 1 : 0; var = fsr_NS =3D ((detect.indexOf("netscape") >=3D0) || = (detect.indexOf("firefox") >=3D0)) ? 1 : 0; if (fsr_NS) = flash_version=3D7; /*Netscape Mozilla supports flash player 7 and = above*/ if (fsr_mac) flash_version=3D8; /*Mac Browsers supports flash = player 8 and above*/ /** FOR MOZILLA BASED BROWSERS - detect flash = plugin & version **/ var = plugin=3D(navigator.mimeTypes&&navigator.mimeTypes["application/x-shockwa= ve-flash"]?navigator.mimeTypes["application/x-shockwave-flash"].enabledPl= ugin:0); if (plugin && = parseInt(plugin.description.substring(plugin.description.indexOf(".")-1))= >=3Dflash_version) { canFlashPlay=3D1; } if ((plugin =3D=3D0 || = plugin=3D=3Dnull) && !canFlashPlay){ triggerParms["displayMode"]=3D1; } = else { /** Skip dhtml invite for the following browsers: ** For Opera = ver 7.5 and below and ** All Netscape Browsers with flash ver < 7 ** Mac = Browsers with flash 7 and below ** Reason: possible bug in browser or = with flash player using wmode ** ** Show Flash for all other browsers = with flash >=3D4 ** Supports IE5+,AOL7+,AOLExplorer,MAC,OPERA8+,FF,NS7+ = **/ if ((fsr_NS && canFlashPlay) || (!fsr_opera75 && canFlashPlay)){ if = (triggerParms["displayMode"]=3D=3D1){ return true; } } = triggerParms["displayMode"]=3D2; } } } if (triggerParms["displayMode"] = >0){ triggerParms["inviteDelay"]=3D 1000; /*overwrite invite timeout to = 1 sec*/ return true; } return false; } function isAlreadyShown(){ = /*check if we already have shown survey or OE Scout Tracker has been = closed*/ if (ForeCStdGetCookie(ckAlreadyShown) !=3D null || = (ForeCStdGetCookie("ScoutRunningCheck") !=3Dnull && = ForeCStdGetCookie("ScoutRunningCheck") =3D=3D "ScoutClosed")) return = true; return false; } function Poll() { if(triggerParms["displayMode"] = =3D=3D 0) { return; } if(currentLocationExcluded()) { return; } var = stickyCounter =3D ForeCStdGetCookie(ckLoyaltyCount); /*check counter = cookie*/ var pageCount; var randNum =3D Math.random(); randNum *=3D 100; = if (stickyCounter =3D=3D null) { pageCount =3D 1; = ForeCStdSetCookie(ckLoyaltyCount, pageCount, = null,'/',triggerParms["domain"]); stickyCounter =3D = ForeCStdGetCookie(ckLoyaltyCount); } if (stickyCounter !=3D null) { = pageCount =3D stickyCounter; if(pageCount >=3D triggerParms["lf"]) { = if(!isAlreadyShown()) { if (triggerParms["rso"] =3D=3D 1 && = triggerParms["aro"] =3D=3D 1) { triggerParms["sp"] =3D 100.0; /*Update = Sample percentage*/ } if(randNum <=3D triggerParms["sp"]) { fsr_aol=3D = ((detect.indexOf("aol") >=3D0) || (detect.indexOf("america online = browser") >=3D0)) ? 1 : 0; fsr_opera =3D (detect.indexOf("opera") >=3D0) = ? 1 : 0; fsr_mac=3D (navigator.platform.indexOf("Win32") >=3D 0) ? 0 : = 1; fsr_NS8=3D(detect.indexOf("netscape/8") >=3D0) ? 1 : 0; = fsr_browser=3D"fsr_nn6"; if(document.all || document.getElementById){ = fsr_browser =3D "fsr_ie"; } if(document.layers) { fsr_browser =3D = "fsr_nn"; } fullURL =3D triggerParms["popupURL"] + "?" + "width=3D" + = triggerParms["width"] + "&height=3D" + triggerParms["height"] + = "&cid=3D" + specialEscape(escape(triggerParms["cid"])) + "&mid=3D" + = specialEscape(escape(triggerParms["mid"])); if ((triggerParms["omb"] ) = !=3D null) { fullURL +=3D "&omb=3D" + escape(triggerParms["omb"]); } if = ((triggerParms["cmetrics"] ) !=3D null) { fullURL +=3D "&cmetrics=3D" + = escape(triggerParms["cmetrics"]); } if (triggerParms["olpu"] =3D=3D 1) { = fullURL +=3D "&olpu=3D1"; } if ((triggerParms["dcUniqueId"]) !=3D null) = { fullURL +=3D "&dcUniqueId=3D" + escape(triggerParms["dcUniqueId"]); } = if (triggerParms["rso"] =3D=3D 1) { fullURL +=3D "&rso=3D1&rct=3D" + = triggerParms["rct"] + "&rds=3D" + triggerParms["rds"] + "&mrd=3D" + = triggerParms["mrd"] + "&rws=3D" + triggerParms["rw"]; } if = ((triggerParms["midexp"] ) !=3D null) { fullURL +=3D = "&ndc=3D1&fsexp=3D5256000&midexp=3D" + triggerParms["midexp"]; } if = (triggerParms["capturePageView"] =3D=3D 1) { triggerParms["cpp_2"] =3D = "PageView:"+ pageCount; /*customer parameter 2 - Page View*/ } = triggerParms["cpp_3"] =3D "Browser:"+ cppUrlPatch (detect) + ";" + = triggerParms["captureTriggerVersion"] +";normal"; if = (triggerParms["visualScienceId"] =3D=3D 1) { = setVisualSciencesId(fullURL); } if (triggerParms["omnitureId"] =3D=3D 1) = { setOmnitureId(fullURL); } var customerParams =3D ""; for(paramKey in = triggerParms) { if(paramKey.substring(0,3) =3D=3D "cpp"){ fullURL +=3D = "&"+ paramKey + "=3D" + escape(triggerParms[paramKey]); } } if = (triggerParms["rso"] !=3D 1) { if(triggerParms["npc"] =3D=3D 1) { = ForeCStdSetCookie(ckAlreadyShown, = 'true',null,'/',triggerParms["domain"]); } else { = ForeCStdSetCookie(ckAlreadyShown, 'true', = persistentExpires,'/',triggerParms["domain"]); } } /*for AOL and Opera = users - show DHTML (by default) because their PopupBlocker behaves = differently*/ if (fsr_aol=3D=3Dfalse && fsr_opera=3D=3Dfalse) { if = (triggerParms["displayMode"]=3D=3D1 || = triggerParms["displayMode"]=3D=3D2){ myPopUp =3D window.open(fullURL, = 'survey',winOptions); } } /** detect flash with valid browser and player = version**/ if (!fsr_mac && (fsr_browser !=3D "fsr_nn") && isValidFlash() = && triggerParms["displayMode"] !=3D2) { document.write("
" + "
"); /*DC I/II = verification*/ if (triggerParms["rso"] =3D=3D 1) { dcQString =3D = "rso=3D1&rct=3D" + triggerParms["rct"] + "&rds=3D" + triggerParms["rds"] = + "&mrd=3D" + triggerParms["mrd"] + "&rws=3D" + triggerParms["rw"]; = if(triggerParms["dcUniqueId"]!=3Dnull) { dcQString +=3D "&dcUniqueId=3D" = + specialEscape(escape(triggerParms["dcUniqueId"])); } } if = ((triggerParms["midexp"] ) !=3D null) { dcQString =3D = "ndc=3D1&midexp=3D" + triggerParms["midexp"] + "&mid=3D" + = specialEscape(escape(triggerParms["mid"])); = if(triggerParms["dcUniqueId"]!=3Dnull) { dcQString +=3D "&dcUniqueId=3D" = + specialEscape(escape(triggerParms["dcUniqueId"])); } } /*Failover = Check*/ surveyProcessCont =3D 1; newDt =3D new Date(); currTime=3D = newDt.getTime(); /*in millisecs*/ OTCImg =3D new Image(); OTCImg.src =3D = null; OTCImg.onerror =3D otcErrorProc; OTCImg.onload =3D otcOnloadProc; = OTCImg.src =3D OTCImgURL + "?protocol=3D" + window.location.protocol + = "&uid=3D"+ currTime; /*for NE/FF Cache Fix*/ } if(myPopUp !=3D null && = !myPopUp.closed) { if (triggerParms["pu"] =3D=3D 1){ self.focus(); } = else { myPopUp.focus();} } } } } pageCount++; = ForeCStdSetCookie(ckLoyaltyCount, pageCount, = null,'/',triggerParms["domain"]); } } ------=_NextPart_000_02DD_01C915A4.4B4988E0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.hhmi.org/js/rollovers/methods.js // roll over OVER function=0A= function rollOver(imgName)=0A= {=0A= if (document.images)=0A= {=0A= document[imgName].src=3Deval(imgName + "over.src");=0A= }=0A= }=0A= =0A= // roll over ON function=0A= function rollOn(imgName)=0A= {=0A= if (document.images)=0A= {=0A= document[imgName].src=3Deval(imgName + "on.src");=0A= }=0A= }=0A= =0A= // roll over OFF function=0A= function rollOff(imgName)=0A= {=0A= if (document.images)=0A= {=0A= document[imgName].src=3Deval(imgName + "off.src");=0A= }=0A= }=0A= // -----------------------=0A= =0A= =0A= =0A= =0A= =0A= =0A= =0A= =0A= =0A= =0A= ------=_NextPart_000_02DD_01C915A4.4B4988E0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.hhmi.org/js/rollovers/shared.js =0A= =0A= // Creating Images and setting up their src properties=0A= if (document.images)=0A= {=0A= =0A= // TOP NAV=0A= btnHome_over =3D new Image=0A= btnHome_over.src =3D"/images/btnHome_over.gif"=0A= btnHome_on =3D new Image=0A= btnHome_on.src =3D"/images/btnHome_on.gif"=0A= btnHome_off =3D new Image=0A= btnHome_off.src =3D"/images/btnHome_off.gif"=0A= =0A= btnAbout_over =3D new Image=0A= btnAbout_over.src =3D"/images/btnAbout_over.gif"=0A= btnAbout_on =3D new Image=0A= btnAbout_on.src =3D"/images/btnAbout_on.gif"=0A= btnAbout_off =3D new Image=0A= btnAbout_off.src =3D"/images/btnAbout_off.gif"=0A= =0A= btnPress_over =3D new Image=0A= btnPress_over.src =3D"/images/btnPress_over.gif"=0A= btnPress_on =3D new Image=0A= btnPress_on.src =3D"/images/btnPress_on.gif"=0A= btnPress_off =3D new Image=0A= btnPress_off.src =3D"/images/btnPress_off.gif"=0A= =0A= btnEmploy_over =3D new Image=0A= btnEmploy_over.src =3D"/images/btnEmploy_over.gif"=0A= btnEmploy_on =3D new Image=0A= btnEmploy_on.src =3D"/images/btnEmploy_on.gif"=0A= btnEmploy_off =3D new Image=0A= btnEmploy_off.src =3D"/images/btnEmploy_off.gif"=0A= =0A= btnContact_over =3D new Image=0A= btnContact_over.src =3D"/images/btnContact_over.gif"=0A= btnContact_on =3D new Image=0A= btnContact_on.src =3D"/images/btnContact_on.gif"=0A= btnContact_off =3D new Image=0A= btnContact_off.src =3D"/images/btnContact_off.gif"=0A= =0A= // HOME -- Context=0A= btnViewCatalog_over =3D new Image=0A= btnViewCatalog_over.src =3D"/images/btnViewCatalog_over.gif"=0A= btnViewCatalog_off =3D new Image=0A= btnViewCatalog_off.src =3D"/images/btnViewCatalog_off.gif"=0A= =0A= // HOME -- Top Nav=0A= btnHomeContext_over =3D new Image=0A= btnHomeContext_over.src =3D"/images/btnHome_over.gif"=0A= btnHomeContext_on =3D new Image=0A= btnHomeContext_on.src =3D"/images/btnHome_on.gif"=0A= btnHomeContext_off =3D new Image=0A= btnHomeContext_off.src =3D"/images/btnHomeContext_off.gif"=0A= =0A= =0A= // ABOUT -- Top Nav=0A= btnAboutContext_over =3D new Image=0A= btnAboutContext_over.src =3D"/images/btnAbout_over.gif"=0A= btnAboutContext_on =3D new Image=0A= btnAboutContext_on.src =3D"/images/btnAbout_on.gif"=0A= btnAboutContext_off =3D new Image=0A= btnAboutContext_off.src =3D"/images/btnAboutContext_off.gif"=0A= =0A= // PRESS -- Top Nav=0A= btnPressContext_over =3D new Image=0A= btnPressContext_over.src =3D"/images/btnPress_over.gif"=0A= btnPressContext_on =3D new Image=0A= btnPressContext_on.src =3D"/images/btnPress_on.gif"=0A= btnPressContext_off =3D new Image=0A= btnPressContext_off.src =3D"/images/btnPressContext_off.gif"=0A= =0A= // CONTACT -- Top Nav=0A= btnContactContext_over =3D new Image=0A= btnContactContext_over.src =3D"/images/btnContact_over.gif"=0A= btnContactContext_on =3D new Image=0A= btnContactContext_on.src =3D"/images/btnContact_on.gif"=0A= btnContactContext_off =3D new Image=0A= btnContactContext_off.src =3D"/images/btnContactContext_off.gif"=0A= =0A= // POPUP=0A= btnCloseWindow_over =3D new Image=0A= btnCloseWindow_over.src =3D"/images/btnCloseWindow_over.gif"=0A= btnCloseWindow_off =3D new Image=0A= btnCloseWindow_off.src =3D"/images/btnCloseWindow_off.gif"=0A= =0A= }=0A= =0A= // roll over OVER function=0A= function rollOver(imgName)=0A= {=0A= if (document.images)=0A= {=0A= document[imgName].src=3Deval(imgName + "over.src");=0A= }=0A= }=0A= =0A= // roll over ON function=0A= function rollOn(imgName)=0A= {=0A= if (document.images)=0A= {=0A= document[imgName].src=3Deval(imgName + "on.src");=0A= }=0A= }=0A= =0A= // roll over OFF function=0A= function rollOff(imgName)=0A= {=0A= if (document.images)=0A= {=0A= document[imgName].src=3Deval(imgName + "off.src");=0A= }=0A= }=0A= // -----------------------=0A= ------=_NextPart_000_02DD_01C915A4.4B4988E0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.hhmi.org/defaults.js default_libs_path =3D "/jslib/";=0A= =0A= =0A= /* This is for Emacs' benefit:=0A= * Local Variables: ***=0A= * mode: Java ***=0A= * End: ***=0A= */=0A= ------=_NextPart_000_02DD_01C915A4.4B4988E0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.hhmi.org/uni_sniff.js // end hide JavaScript=0A= ------=_NextPart_000_02DD_01C915A4.4B4988E0 Content-Type: application/octet-stream Content-Transfer-Encoding: quoted-printable Content-Location: http://www.hhmi.org/libloader.js /*=0A= =0A= libloader.js - load JavaScript libraries based on browser type=0A= =0A= NOTE: Requires that the "Ultimate client-side JavaScript client=0A= sniff" from Netscape (or its equivalent) be already loaded, as=0A= this makes decisions based on the sniff's results.=0A= =0A= NOTE: If you neither pass in a libs_path argument nor override=0A= default_libs_path before you call load_library, it will default to=0A= computing library filenames relative to the current path. That=0A= means that each library should have its own directory in the=0A= current path, e.g., object_access/, object_position/, etc.=0A= =0A= You probably -really- want to go ahead and set a library path, for=0A= cleanliness' sake.=0A= =0A= NOTE: If default_libs_path or a libs_path argument is non-empty,=0A= it MUST end with a slash ("/"), since I don't really want to hack=0A= around to check for that right now. Maybe later, when I'm feeling=0A= more user-friendly.=0A= =0A= NOTE: This is the one library (apart from uni_sniff, of course)=0A= that will probably have nasty, hackish, per-browser checking,=0A= because it can't rely on any generalized functionality having been=0A= loaded yet. However, I try to rely on as little mojo as possible=0A= here (get_global being the only place I'm aware of needing to=0A= abstract away anything, and that happens to be the same across all=0A= browsers right now) in an effort to keep things clean.=0A= =0A= However, note that _make_libpath has some nasty hardcoded rules to=0A= compute the library filename. Those rules are (at present)=0A= necessary because of the way uni_sniff computes its various=0A= variables. We can't just look through the namespace and snatch out=0A= "is_" variables that are true. We actually have to know something=0A= about the various quirks of how browsers are named and how=0A= compatible they are (or aren't). At some point, we'll codify this=0A= in a snazzy data structure, but that day ain't today.=0A= =0A= */=0A= =0A= // We check, just in case someone defined default_libs_path -before-=0A= // loading this script (or loaded this script multiple times?)=0A= if (! default_libs_path) var default_libs_path =3D "";=0A= =0A= =0A= /* All browsers do this the same way, so we're safe defining it here. */=0A= function get_global (name) {=0A= return window[name];=0A= }=0A= =0A= =0A= function library_loaded (name) {=0A= debug.writeln("library_loaded: " + name + " [" + get_global("lib_" + = name) + "]");=0A= return get_global("lib_" + name);=0A= }=0A= =0A= =0A= function library_load (name, libs_path) {=0A= if (library_loaded(name)) return 1;=0A= var libpath =3D _make_libpath(name, libs_path);=0A= document.write('